Infertility and problems of impaired fecundity have been a concern through ages and is also a significant clinical problem today, which affects 8–12% of couples worldwide. (Kumar N., 2015). However, genetic abnormalities in the genes that control numerous biological processes implicated in gametogenesis, maintenance of sperm/ ovarian reserve, hormonal signaling, and anatomical and functional development of reproductive organs are associated with infertility.

Genetic factors contribute upto 15%–30% cases of male infertility (Shamshi MB, 2011). These include:

Female factors account for at least 35% of all infertility cases and comprise a wide range of causes including:

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